Castilla–La Mancha (UK: /kæˌstiːjə læ ˈmæntʃə/, US: /- lɑː ˈmɑːntʃə/, Spanish: [kasˈtiʎa la ˈmantʃa], or Castile La Mancha, is an autonomous community of Spain. Comprising the provinces of Albacete, Ciudad Real, Cuenca, Guadalajara and Toledo, it was created in 1982. The government headquarters are in Toledo, and its largest city is in Albacete.

The region largely occupies the southern half of the Iberian Peninsula’s Inner Plateau, including large parts of the catchment areas of the Tagus, the Guadiana and the Júcar, while the northeastern relief comprises the Sistema Ibérico mountain massif.

It is bordered by Castile and León, Madrid, Aragon, Valencia, Murcia, Andalusia, and Extremadura. It is one of the most sparsely populated of Spain’s regions. Albacete, Guadalajara, Toledo, Talavera de la Reina and Ciudad Real concentrate the largest urban areas in the region.