Some of its tourism highlights include the walls of Ávila, and the cathedrals of Burgos and Leon.

Castile and León has several cities whose Holy Week is considered to be of International Tourist Interest. Examples are Holy Week in León, Holy Week in Salamanca, Holy Week in Valladolid or Holy Week in Zamora.

The region also has a wide network of Paradores, hotels of great quality that usually accommodate buildings of great historical value in privileged places to stimulate tourism in the area.

Since 1988, the foundation Las Edades del Hombre has been organizing various exhibitions of religious art in various parts of the national and international geography, highlighting for its interest the exhibitions held in Castile and León. The idea of carrying out these exhibitions was conceived in a chimney of Alcazarén with the writer José Jiménez Lozano and the priest of Valladolid José Velicia. The first “Las Edades del Hombre” were held in the Church of Santiago Apóstol of Alcazarén, with a small exhibition of sacred paintings. Later, and with the support of important personalities, the first known exhibition was held among the public, which was that of Valladolid. In 2012 the initiative was developed under the name of Monacatus in the town of Oña, being one of the most multitudinous editions with about 200 000 visitors. The last sample so far has taken place in the municipality of Arévalo, in 2013. With the title of Credo, the exhibition has revolved around the faith and has received more than 226 000 visitors.