In the 1960s, Gran Canaria was selected as the location for one of the 14 ground stations in the Manned Space Flight Network (MSFN) to support the NASA space program. Maspalomas Station, located in the south of the island, took part in a number of space missions including the Apollo 11 Moon landings and Skylab. Today it continues to support satellite communications as part of the ESA network.

Because of the remote location, a number of astronomical observatories are located in the archipelago, including the Teide Observatory on Tenerife, the Roque de los Muchachos Observatory on La Palma, and the Temisas Astronomical Observatory on Gran Canaria.

Tenerife is the home of the Instituto de Astrofísica de Canarias (Astrophysical Institute of the Canaries). There is also an Instituto de Bio-Orgánica Antonio González (Antonio González Bio-Organic Institute) at the University of La Laguna. Also at that university are the Instituto de Lingüística Andrés Bello (Andrés Bello Institute of Linguistics), the Centro de Estudios Medievales y Renacentistas (Center for Medieval and Renaissance Studies), the Instituto Universitario de la Empresa (University Institute of Business), the Instituto de Derecho Regional (Regional Institute of Law), the Instituto Universitario de Ciencias Políticas y Sociales (University Institute of Political and Social Sciences) and the Instituto de Enfermedades Tropicales (Institute of Tropical Diseases). The latter is one of the seven institutions of the Red de Investigación de Centros de Enfermedades Tropicales (RICET, “Network of Research of Centers of Tropical Diseases”), located in various parts of Spain. The Instituto Volcanológico de Canarias (Volcanological Institute of the Canary Islands) is based in Tenerife.